The precise prevalence of GSDVI is unknown. A minimum of 11 instances have been reported within the medical literature, although this condition is more likely to be underdiagnosed as a result of it may be troublesome to detect in kids with mild signs or adults with no signs. GSDVI is more frequent within the Old Older Mennonite population, with an estimated incidence of 1 in 1,000 people. Mutations within the PYGL gene cause GSDVI. The PYGL gene supplies directions for Healthy Flow Blood pills making an enzyme known as liver glycogen phosphorylase. This enzyme is found only in liver cells, where it breaks down glycogen into a type of sugar called glucose-1-phosphate. Additional steps convert glucose-1-phosphate into glucose, a simple sugar that is the main energy source for most cells within the physique. PYGL gene mutations stop liver glycogen phosphorylase from breaking down glycogen successfully. Because liver cells can not break down glycogen into glucose, people with GSDVI can have hypoglycemia and will use fats for vitality, leading to ketosis.